# OnCo record tpextreme (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/tpextreme/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "tpextreme", "NCT02268695" ;
  schema:name "TPExtreme (GORTEC 2014-01)"@en ;
  schema:alternateName "TPExtreme"@en, "GORTEC 2014-01"@en ;
  schema:description "TPExtreme compared a shorter, docetaxel-based version of the standard EXTREME chemotherapy for advanced head and neck cancer with the original; patients lived about as long on either, and the shorter regimen was easier to tolerate, so it became an accepted alternative."@en ;
  schema:url <https://onco.cc/trials/tpextreme/> ;
  schema:dateModified "2026-09-17"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT02268695> ;
  onco:status "mixed" ;
  onco:tag "subtype-trials" ;
  onco:phase "2" ;
  onco:cancers <https://onco.cc/cancers/recurrent-metastatic-hnscc/>, <https://onco.cc/cancers/head-and-neck/> ;
  onco:drugs <https://onco.cc/drugs/docetaxel/>, <https://onco.cc/drugs/cisplatin/>, <https://onco.cc/drugs/cetuximab/>, <https://onco.cc/drugs/fluorouracil/> ;
  onco:people <https://onco.cc/people/joel-guigay/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-tpextreme-lancet-oncol-2021/> .