# OnCo record trastuzumab-brengitecan (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/trastuzumab-brengitecan/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "trastuzumab-brengitecan" ;
  schema:name "Trastuzumab brengitecan"@en ;
  schema:description "SystImmune's HER2 ADC, sharing its payload with iza-bren, now in a 1,450-patient trial to replace Kadcyla after surgery."@en ;
  schema:url <https://onco.cc/drugs/trastuzumab-brengitecan/> ;
  schema:dateModified "2026-09-07"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT04622319> ;
  onco:status "phase-3" ;
  onco:modality "ADC" ;
  onco:cancers <https://onco.cc/cancers/breast-her2-positive/> ;
  onco:technologies <https://onco.cc/technologies/adc/>, <https://onco.cc/technologies/topoisomerase-inhibitors/> ;
  onco:targets <https://onco.cc/targets/her2/> ;
  onco:companies <https://onco.cc/companies/systimmune/> ;
  onco:trials <https://onco.cc/trials/destiny-breast05/>, <https://onco.cc/trials/nct07518173/>, <https://onco.cc/trials/nct06830889/>, <https://onco.cc/trials/nct06316531/>, <https://onco.cc/trials/nct07178795/>, <https://onco.cc/trials/nct06891833/>, <https://onco.cc/trials/nct06114511/>, <https://onco.cc/trials/nct06445400/>, <https://onco.cc/trials/nct07264816/> .