# OnCo record tremelimumab (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/tremelimumab/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "tremelimumab" ;
  schema:name "Tremelimumab"@en ;
  schema:description "Tremelimumab is AstraZeneca's CTLA-4 antibody, given as a single priming dose with durvalumab and chemotherapy in lung and liver cancer."@en ;
  schema:url <https://onco.cc/drugs/tremelimumab/> ;
  schema:dateModified "2026-09-06"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Tremelimumab> ;
  owl:sameAs <http://www.wikidata.org/entity/Q7838098> ;
  schema:citation <https://dailymed.nlm.nih.gov/dailymed/search.cfm?query=Tremelimumab> ;
  onco:status "approved" ;
  onco:modality "Monoclonal antibody (anti-CTLA-4)" ;
  schema:alternateName "Imjudo" ;
  onco:approval "US 2022: Metastatic NSCLC without EGFR/ALK, with durvalumab and platinum chemotherapy; unresectable HCC with durvalumab" ;
  onco:cancers <https://onco.cc/cancers/nsclc/>, <https://onco.cc/cancers/hcc/>, <https://onco.cc/cancers/hcc-advanced/>, <https://onco.cc/cancers/limited-stage-sclc/> ;
  onco:technologies <https://onco.cc/technologies/checkpoint-inhibitor/> ;
  onco:targets <https://onco.cc/targets/ctla4/> ;
  onco:drugs <https://onco.cc/drugs/durvalumab/> ;
  onco:companies <https://onco.cc/companies/astrazeneca/> ;
  onco:trials <https://onco.cc/trials/nct06921785/>, <https://onco.cc/trials/nct03164616/>, <https://onco.cc/trials/nct05883644/>, <https://onco.cc/trials/nct05557838/>, <https://onco.cc/trials/nct07081633/>, <https://onco.cc/trials/nct01843374/>, <https://onco.cc/trials/nct02519348/>, <https://onco.cc/trials/nct03682068/>, <https://onco.cc/trials/nct06008093/>, <https://onco.cc/trials/nct02516241/>, <https://onco.cc/trials/nct02453282/>, <https://onco.cc/trials/nct03837899/>, <https://onco.cc/trials/nct02542293/>, <https://onco.cc/trials/nct04960709/> .