# OnCo record tretinoin-atra (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/tretinoin-atra/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "tretinoin-atra" ;
  schema:name "Tretinoin (all-trans retinoic acid, ATRA)"@en ;
  schema:alternateName "All-trans retinoic acid"@en, "ATRA"@en, "Retinoic acid"@en, "Vesanoid" ;
  schema:description "The vitamin-A derivative that made acute promyelocytic leukaemia the first cancer cured by differentiation therapy rather than by killing cells."@en ;
  schema:url <https://onco.cc/drugs/tretinoin-atra/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Tretinoin> ;
  owl:sameAs <http://www.wikidata.org/entity/Q29417> ;
  schema:citation <https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=tretinoin%20capsules> ;
  onco:status "approved" ;
  onco:tag "gap-fill" ;
  onco:modality "Oral retinoid (differentiation agent)" ;
  onco:approval "US 1995: Induction of remission in APL (t(15;17)/PML-RARA)" ;
  onco:cancers <https://onco.cc/cancers/aml/>, <https://onco.cc/cancers/apl/> ;
  onco:technologies <https://onco.cc/technologies/epigenetic-drugs/> ;
  onco:companies <https://onco.cc/companies/roche-genentech/> ;
  onco:terms <https://onco.cc/terms/differentiation-syndrome/> .