# OnCo record trial-lifecycle (term). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/terms/trial-lifecycle/>
  a schema:DefinedTerm ;
  onco:kind "term" ;
  schema:identifier "trial-lifecycle" ;
  schema:name "Trial lifecycle: from protocol to label"@en ;
  schema:alternateName "trial lifecycle"@en, "life cycle of a trial"@en, "how a trial works"@en, "stages of a trial"@en, "from bench to bedside"@en, "IND application"@en, "investigational new drug application"@en, "clinical trial application"@en, "CTA"@en, "site activation"@en, "site initiation"@en, "first patient in"@en, "first patient dosed"@en, "last patient in"@en, "last patient last visit"@en, "database lock"@en, "topline readout"@en, "primary completion"@en, "primary completion date"@en, "study completion"@en, "congress presentation"@en, "late-breaking abstract"@en, "peer-reviewed publication"@en, "regulatory submission"@en, "filing"@en, "label expansion"@en, "approval"@en, "post-marketing"@en, "phase 4"@en, "long-term follow-up study"@en ;
  schema:description "A trial moves through a fixed sequence: a written protocol, regulatory and ethics approval, public registration, opening sites and enrolling patients, independent monitoring while it runs, readout when enough events have happened, presentation and publication, and, if it succeeds, a change to the drug's label and to guidelines."@en ;
  schema:url <https://onco.cc/terms/trial-lifecycle/> ;
  schema:dateModified "2026-09-17"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Clinical_trial> ;
  schema:citation <https://en.wikipedia.org/wiki/Clinical_trial>, <https://clinicaltrials.gov/>, <https://www.ich.org/page/efficacy-guidelines> ;
  onco:related <https://onco.cc/terms/trial-phases/>, <https://onco.cc/terms/trial-protocol/>, <https://onco.cc/terms/ethics-review/>, <https://onco.cc/terms/informed-consent/>, <https://onco.cc/terms/trial-registration/>, <https://onco.cc/terms/accrual/>, <https://onco.cc/terms/data-monitoring-committee/>, <https://onco.cc/terms/interim-analysis/>, <https://onco.cc/terms/pivotal-trial/>, <https://onco.cc/terms/confirmatory-trial/>, <https://onco.cc/terms/bla-nda/>, <https://onco.cc/terms/label-indication/>, <https://onco.cc/terms/accelerated-approval/>, <https://onco.cc/terms/regulatory-agencies/>, <https://onco.cc/terms/first-in-human/> ;
  onco:sections <https://onco.cc/fronts/drug-discovery/> ;
  onco:trials <https://onco.cc/trials/keynote-522/>, <https://onco.cc/trials/adaura/>, <https://onco.cc/trials/navigate/>, <https://onco.cc/trials/announce/>, <https://onco.cc/trials/atlantis/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-trial-design/>, <https://onco.cc/bottlenecks/b-trial-enrolment/> .