# OnCo record trifluridine-tipiracil (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/trifluridine-tipiracil/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "trifluridine-tipiracil" ;
  schema:name "Trifluridine/tipiracil"@en ;
  schema:description "An oral chemotherapy pill for bowel cancer that has stopped responding to everything else; with bevacizumab it extends life by about three months."@en ;
  schema:url <https://onco.cc/drugs/trifluridine-tipiracil/> ;
  schema:dateModified "2026-09-07"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Trifluridine/tipiracil> ;
  owl:sameAs <http://www.wikidata.org/entity/Q15708335> ;
  schema:citation <https://www.accessdata.fda.gov/drugsatfda_docs/label/2023/207981s012lbl.pdf>, <https://www.nice.org.uk/guidance/ta405>, <https://www.nice.org.uk/guidance/ta1008>, <https://www.ema.europa.eu/en/medicines/human/EPAR/lonsurf> ;
  onco:status "approved" ;
  onco:modality "Cytotoxic chemotherapy (oral nucleoside)" ;
  schema:alternateName "Lonsurf" ;
  onco:approval "US 2015: Refractory metastatic colorectal cancer", "US 2019: Refractory metastatic gastric/GEJ cancer (TAGS)", "US 2023: Refractory mCRC with bevacizumab", "EU 2016: Metastatic colorectal cancer after available therapies", "England (NICE) 2016: Previously treated metastatic colorectal cancer", "England (NICE) 2024: Metastatic colorectal cancer after two lines of treatment, with bevacizumab" ;
  onco:cancers <https://onco.cc/cancers/colorectal/>, <https://onco.cc/cancers/gastric/> ;
  onco:technologies <https://onco.cc/technologies/cytotoxic-chemotherapy/> ;
  onco:companies <https://onco.cc/companies/servier/>, <https://onco.cc/companies/takeda/> ;
  onco:trials <https://onco.cc/trials/sunlight/>, <https://onco.cc/trials/circulate-japan/>, <https://onco.cc/trials/nct06199973/>, <https://onco.cc/trials/nct07361003/>, <https://onco.cc/trials/nct06873763/>, <https://onco.cc/trials/nct04701476/>, <https://onco.cc/trials/nct05919264/>, <https://onco.cc/trials/nct06992258/>, <https://onco.cc/trials/nct05405595/>, <https://onco.cc/trials/nct07280377/>, <https://onco.cc/trials/nct04626635/>, <https://onco.cc/trials/recourse/>, <https://onco.cc/trials/altair/> .