# OnCo record tropion-lung05 (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/tropion-lung05/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "tropion-lung05", "NCT04484142" ;
  schema:name "TROPION-Lung05"@en ;
  schema:description "The study that got Datroway approved for EGFR-mutant lung cancer after other treatments fail."@en ;
  schema:url <https://onco.cc/trials/tropion-lung05/> ;
  schema:dateModified "2026-09-06"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT04484142> ;
  onco:status "positive" ;
  onco:phase "2" ;
  schema:startDate "2021-03-30" ;
  onco:cancers <https://onco.cc/cancers/nsclc/>, <https://onco.cc/cancers/egfr-mutant-nsclc/> ;
  onco:technologies <https://onco.cc/technologies/adc/>, <https://onco.cc/technologies/topoisomerase-inhibitors/> ;
  onco:targets <https://onco.cc/targets/trop2/>, <https://onco.cc/targets/egfr/> ;
  onco:drugs <https://onco.cc/drugs/datopotamab-deruxtecan/> ;
  onco:companies <https://onco.cc/companies/astrazeneca/>, <https://onco.cc/companies/daiichi-sankyo/> ;
  onco:trials <https://onco.cc/trials/tropion-lung01/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-tropion-lung05-j-clin-oncol-2025/> .