# OnCo record ttf1-p40 (term). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/terms/ttf1-p40/>
  a schema:DefinedTerm ;
  onco:kind "term" ;
  schema:identifier "ttf1-p40" ;
  schema:name "TTF-1 and p40 (how lung histology is decided)"@en ;
  schema:alternateName "TTF-1"@en, "TTF1"@en, "p40"@en, "thyroid transcription factor 1"@en, "TTF-1 and p40 panel"@en, "NSCLC-NOS"@en ;
  schema:description "The two stains that decide whether a poorly differentiated lung cancer is called adenocarcinoma or squamous cell carcinoma. TTF-1 positive with p40 negative means adenocarcinoma; p40 positive with TTF-1 negative means squamous. The answer decides whether the tumour is sequenced and which drugs are safe."@en ;
  schema:url <https://onco.cc/terms/ttf1-p40/> ;
  schema:dateModified "2026-09-25"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Thyroid_transcription_factor_1> ;
  schema:citation <https://doi.org/10.1016/j.jtho.2021.11.003>, <https://www.nice.org.uk/guidance/ng122/chapter/Diagnosis-and-staging> ;
  onco:tag "lung" ;
  onco:cancers <https://onco.cc/cancers/nsclc/>, <https://onco.cc/cancers/lung-adenocarcinoma/>, <https://onco.cc/cancers/lung-squamous-cell-carcinoma/>, <https://onco.cc/cancers/large-cell-lung-carcinoma/>, <https://onco.cc/cancers/lung-lcnec/>, <https://onco.cc/cancers/lung-cancer/> ;
  onco:technologies <https://onco.cc/technologies/histopathology-ihc/>, <https://onco.cc/technologies/cgp/> ;
  onco:terms <https://onco.cc/terms/spread-through-air-spaces/>, <https://onco.cc/terms/ebus-tbna/>, <https://onco.cc/terms/tumour-differentiation/> .