# OnCo record ttk (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/ttk/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "ttk" ;
  schema:name "MPS1 (TTK)"@en ;
  schema:alternateName "MPS1"@en, "Mps1"@en, "TTK protein kinase"@en, "PYT"@en, "CT96"@en, "TTK" ;
  schema:description "MPS1 arms the checkpoint that holds a dividing cell until its chromosomes are attached. Blocking it lets cancer cells divide carelessly and die; one inhibitor is in phase 1/2 in breast cancer."@en ;
  schema:url <https://onco.cc/targets/ttk/> ;
  schema:dateModified "2026-09-24"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:12401>, <https://www.uniprot.org/uniprotkb/P33981/entry>, <https://www.ncbi.nlm.nih.gov/gene/7272>, <https://clinicaltrials.gov/study/NCT05251714> ;
  onco:tag "checkpoint-map" ;
  onco:targetClass "kinase" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:12401>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000112742>, <https://www.uniprot.org/uniprotkb/P33981/entry>, <https://www.ncbi.nlm.nih.gov/gene/7272> ;
  onco:related <https://onco.cc/targets/bub1/>, <https://onco.cc/targets/aurkb/>, <https://onco.cc/targets/aurka/> ;
  onco:cancers <https://onco.cc/cancers/breast-hr-positive/> ;
  onco:pathways <https://onco.cc/pathways/mitotic-spindle-checkpoint/> .