# OnCo record tuberous-sclerosis-complex (term). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/terms/tuberous-sclerosis-complex/>
  a schema:DefinedTerm ;
  onco:kind "term" ;
  schema:identifier "tuberous-sclerosis-complex" ;
  schema:name "Tuberous sclerosis complex"@en ;
  schema:alternateName "TSC"@en, "tuberous sclerosis"@en ;
  schema:description "Tuberous sclerosis complex is an inherited condition, caused by a fault in TSC1 or TSC2, that grows non-cancerous tumours in the brain, kidneys, heart and skin and raises the risk of kidney cancer. Regular brain and kidney scans guide treatment, and tablets called mTOR inhibitors shrink several of these tumours."@en ;
  schema:url <https://onco.cc/terms/tuberous-sclerosis-complex/> ;
  schema:dateModified "2026-11-04"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Tuberous_sclerosis> ;
  schema:citation <https://doi.org/10.1158/1078-0432.ccr-24-1947>, <https://doi.org/10.1016/j.pediatrneurol.2021.07.011>, <https://www.orpha.net/en/disease/detail/805>, <https://www.england.nhs.uk/wp-content/uploads/2018/08/rare-and-inherited-disease-national-genomics-test-directory-v9.xlsx> ;
  onco:tag "gap-fill", "hereditary" ;
  onco:cancers <https://onco.cc/cancers/pecoma/>, <https://onco.cc/cancers/rcc/> ;
  onco:technologies <https://onco.cc/technologies/germline-testing/> ;
  onco:targets <https://onco.cc/targets/tsc1/>, <https://onco.cc/targets/tsc2/> ;
  onco:drugs <https://onco.cc/drugs/everolimus/> ;
  onco:terms <https://onco.cc/terms/hereditary-cancer-syndromes/> .