# OnCo record tubulin (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/tubulin/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "tubulin" ;
  schema:name "Tubulin (microtubules)"@en ;
  schema:description "The protein that builds the microtubule scaffolding a cell needs to pull its chromosomes apart. Taxanes freeze the scaffold and vinca alkaloids and eribulin stop it forming; either way the dividing cell stalls and dies."@en ;
  schema:url <https://onco.cc/targets/tubulin/> ;
  schema:dateModified "2026-09-04"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Tubulin>, <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:20778>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000196230>, <https://www.uniprot.org/uniprotkb/P07437/entry>, <https://www.ncbi.nlm.nih.gov/gene/203068> ;
  schema:citation <https://www.uniprot.org/uniprotkb/P07437/entry> ;
  schema:alternateName "TUBB" ;
  onco:targetClass "other" ;
  onco:firstDescribed "1983"^^xsd:gYear ;
  onco:cancers <https://onco.cc/cancers/breast-hr-positive/>, <https://onco.cc/cancers/nsclc/>, <https://onco.cc/cancers/ovarian/>, <https://onco.cc/cancers/all-leukemia/> ;
  onco:drugs <https://onco.cc/drugs/paclitaxel/>, <https://onco.cc/drugs/docetaxel/>, <https://onco.cc/drugs/vincristine/>, <https://onco.cc/drugs/eribulin/> .