# OnCo record tucatinib-triplet-brain-mets (pairing). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/pairings/tucatinib-triplet-brain-mets/>
  a schema:MedicalTherapy ;
  onco:kind "pairing" ;
  schema:identifier "tucatinib-triplet-brain-mets" ;
  schema:name "Tucatinib + trastuzumab + capecitabine for brain metastases"@en ;
  schema:description "The one regimen proven in a randomised trial to help HER2-positive brain metastases, extending survival in those patients by six months."@en ;
  schema:url <https://onco.cc/pairings/tucatinib-triplet-brain-mets/> ;
  schema:dateModified "2026-09-07"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT02614794> ;
  onco:cancers <https://onco.cc/cancers/breast-her2-positive/> ;
  onco:drugs <https://onco.cc/drugs/tucatinib/>, <https://onco.cc/drugs/trastuzumab/> ;
  onco:terms <https://onco.cc/terms/her2-brain-metastases/> ;
  onco:trials <https://onco.cc/trials/her2climb/> ;
  onco:pairs <https://onco.cc/drugs/tucatinib/>, <https://onco.cc/drugs/trastuzumab/> .