# OnCo record tyk2 (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/tyk2/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "tyk2" ;
  schema:name "TYK2"@en ;
  schema:alternateName "tyrosine kinase 2"@en, "Non-receptor tyrosine-protein kinase TYK2"@en, "JTK1"@en, "TYK2" ;
  schema:description "TYK2 (Non-receptor tyrosine-protein kinase TYK2) is a protein kinase, an enzyme that switches other proteins on by adding phosphate groups. The public catalogues list it as a drug target and a biomarker, and an approved or late-stage drug is recorded against it. Tied to Myeloproliferative neoplasms, Malignant peripheral nerve sheath tumour and Polycythaemia vera."@en ;
  schema:url <https://onco.cc/targets/tyk2/> ;
  schema:dateModified "2026-09-23"^^xsd:date ;
  schema:citation <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:12440>, <https://www.uniprot.org/uniprotkb/P29597/entry>, <https://www.ncbi.nlm.nih.gov/gene/7297>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000105397> ;
  onco:tag "cancer-genes-wave" ;
  onco:targetClass "kinase" ;
  schema:sameAs <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:12440>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000105397>, <https://www.uniprot.org/uniprotkb/P29597/entry>, <https://www.ncbi.nlm.nih.gov/gene/7297> ;
  onco:related <https://onco.cc/collections/civic/>, <https://onco.cc/collections/open-targets/> ;
  onco:cancers <https://onco.cc/cancers/myeloproliferative-neoplasms/>, <https://onco.cc/cancers/malignant-peripheral-nerve-sheath-tumour/>, <https://onco.cc/cancers/polycythaemia-vera/> .