# OnCo record ugt1a1-genotyping (technology). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/technologies/ugt1a1-genotyping/>
  a schema:MedicalTherapy ;
  onco:kind "technology" ;
  schema:identifier "ugt1a1-genotyping" ;
  schema:name "UGT1A1 genotyping before irinotecan"@en ;
  schema:alternateName "UGT1A1*28"@en, "UGT1A1*6"@en, "Gilbert syndrome genotype"@en, "irinotecan pharmacogenetics"@en ;
  schema:description "A gene test that finds people who clear irinotecan's active form slowly because of a common variant in the UGT1A1 enzyme, the same variant behind harmless Gilbert syndrome; they run a higher risk of severe diarrhoea and low white cells at full dose."@en ;
  schema:url <https://onco.cc/technologies/ugt1a1-genotyping/> ;
  schema:dateModified "2026-09-17"^^xsd:date ;
  schema:citation <https://www.pharmgkb.org> ;
  onco:status "established" ;
  onco:cancers <https://onco.cc/cancers/colorectal/>, <https://onco.cc/cancers/pancreatic/>, <https://onco.cc/cancers/gastric/>, <https://onco.cc/cancers/sclc/>, <https://onco.cc/cancers/tnbc/>, <https://onco.cc/cancers/urothelial/> ;
  onco:sections <https://onco.cc/fronts/diagnostics/>, <https://onco.cc/fronts/chemotherapy/>, <https://onco.cc/fronts/supportive-care/> ;
  onco:technologies <https://onco.cc/technologies/oncology-pharmacogenomics/>, <https://onco.cc/technologies/germline-testing/>, <https://onco.cc/technologies/dpyd-genotyping/>, <https://onco.cc/technologies/tpmt-nudt15-genotyping/> ;
  onco:drugs <https://onco.cc/drugs/irinotecan/>, <https://onco.cc/drugs/sacituzumab-govitecan/> ;
  onco:terms <https://onco.cc/terms/dose-modification/>, <https://onco.cc/terms/neutropenia/>, <https://onco.cc/terms/febrile-neutropenia/>, <https://onco.cc/terms/pharmacokinetics/> .