# OnCo record ukallr3 (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/ukallr3/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "ukallr3", "NCT00967057" ;
  schema:name "ALL R3 (UKALLR3)"@en ;
  schema:alternateName "UKALLR3"@en, "ALLR3"@en, "ALL R3"@en, "CCLG-ALLR3"@en ;
  schema:description "ALL R3 found, to the investigators' surprise, that using mitoxantrone instead of idarubicin in the first block of treatment for children whose leukaemia had relapsed nearly doubled the chance of being alive without progression three years later, and mitoxantrone-based reinduction became the standard."@en ;
  schema:url <https://onco.cc/trials/ukallr3/> ;
  schema:dateModified "2026-09-22"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT00967057> ;
  onco:status "positive" ;
  onco:tag "soc-trials" ;
  onco:phase "3" ;
  onco:cancers <https://onco.cc/cancers/all-paediatric-relapsed/>, <https://onco.cc/cancers/all-leukemia/>, <https://onco.cc/cancers/leukaemia/> ;
  onco:technologies <https://onco.cc/technologies/cytotoxic-chemotherapy/>, <https://onco.cc/technologies/mrd-testing/> ;
  onco:drugs <https://onco.cc/drugs/mitoxantrone/>, <https://onco.cc/drugs/idarubicin/>, <https://onco.cc/drugs/dexamethasone/>, <https://onco.cc/drugs/asparaginase/>, <https://onco.cc/drugs/methotrexate/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-all-r3-mitoxantrone-relapsed-childhood-all-parker-lancet-2010/> .