# OnCo record umbrella-trial (term). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/terms/umbrella-trial/>
  a schema:DefinedTerm ;
  onco:kind "term" ;
  schema:identifier "umbrella-trial" ;
  schema:name "Umbrella trial"@en ;
  schema:alternateName "umbrella trial"@en, "umbrella trials"@en, "umbrella study"@en, "umbrella design"@en, "umbrella protocol"@en, "one cancer many drugs"@en, "biomarker-matched sub-studies"@en, "sub-study"@en, "sub-studies"@en, "substudy"@en, "substudies"@en, "screening protocol"@en, "molecular screening protocol"@en, "genomic screening protocol"@en, "treatment arm assignment"@en ;
  schema:description "An umbrella trial takes one cancer, tests every patient's tumour for a panel of markers, and routes each patient to the sub-study whose drug matches their marker, so several targeted drugs are tested at once under one roof."@en ;
  schema:url <https://onco.cc/terms/umbrella-trial/> ;
  schema:dateModified "2026-09-17"^^xsd:date ;
  schema:citation <https://doi.org/10.1056/NEJMra1510062> ;
  onco:related <https://onco.cc/terms/basket-umbrella-platform/>, <https://onco.cc/terms/basket-trial/>, <https://onco.cc/terms/seamless-adaptive/>, <https://onco.cc/terms/biomarker-stratified-design/>, <https://onco.cc/terms/mrd/>, <https://onco.cc/terms/single-arm/>, <https://onco.cc/terms/trial-protocol/> ;
  onco:sections <https://onco.cc/fronts/drug-discovery/> ;
  onco:trials <https://onco.cc/trials/myelomatch/>, <https://onco.cc/trials/pediatric-match/>, <https://onco.cc/trials/stampede/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-trial-design/>, <https://onco.cc/bottlenecks/b-trial-enrolment/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-woodcock-n-engl-j-med/> .