# OnCo record vaccine-plus-pd1 (pairing). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/pairings/vaccine-plus-pd1/>
  a schema:MedicalTherapy ;
  onco:kind "pairing" ;
  schema:identifier "vaccine-plus-pd1" ;
  schema:name "Personalised neoantigen vaccine + PD-1 blockade"@en ;
  schema:description "The vaccine teaches the immune system what to hunt; PD-1 blockade stops the tumour from switching the hunters off."@en ;
  schema:url <https://onco.cc/pairings/vaccine-plus-pd1/> ;
  schema:dateModified "2026-09-04"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT05933577> ;
  onco:cancers <https://onco.cc/cancers/melanoma/>, <https://onco.cc/cancers/pancreatic/> ;
  onco:drugs <https://onco.cc/drugs/intismeran-autogene/>, <https://onco.cc/drugs/pembrolizumab/>, <https://onco.cc/drugs/autogene-cevumeran/> ;
  onco:pathways <https://onco.cc/pathways/pd1-checkpoint/> ;
  onco:trials <https://onco.cc/trials/interpath-001/> ;
  onco:pairs <https://onco.cc/technologies/neoantigen-mrna-vaccine/>, <https://onco.cc/technologies/checkpoint-inhibitor/> .