# OnCo record vaginal-adenocarcinoma (cancer). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/cancers/vaginal-adenocarcinoma/>
  a schema:MedicalCondition ;
  onco:kind "cancer" ;
  schema:identifier "vaginal-adenocarcinoma" ;
  schema:name "Vaginal adenocarcinoma (including DES-associated clear cell adenocarcinoma)"@en ;
  schema:alternateName "Clear cell adenocarcinoma of the vagina"@en, "DES-associated vaginal cancer"@en, "Vaginal adenocarcinoma"@en, "Mesonephric and endometrioid adenocarcinoma of the vagina"@en ;
  schema:description "Vaginal adenocarcinoma is a rare glandular form of vaginal cancer, best known through the clear cell type that struck young women whose mothers took the hormone DES in pregnancy. Unlike the common squamous form it is not caused by HPV, it is treated with surgery where possible because it often affects young women, and radiotherapy and platinum chemotherapy are used when it is advanced."@en ;
  schema:url <https://onco.cc/cancers/vaginal-adenocarcinoma/> ;
  schema:dateModified "2026-09-18"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Vaginal_cancer> ;
  schema:citation <https://doi.org/10.1056/NEJM197104222841604>, <https://en.wikipedia.org/wiki/Vaginal_cancer> ;
  onco:tag "subtype-page", "gynaecologic" ;
  onco:related <https://onco.cc/cancers/vaginal-squamous-cell-carcinoma/>, <https://onco.cc/cancers/vaginal/>, <https://onco.cc/cancers/clear-cell-ovarian-cancer/> ;
  onco:technologies <https://onco.cc/technologies/brachytherapy/>, <https://onco.cc/technologies/imrt-igrt/>, <https://onco.cc/technologies/histopathology-ihc/>, <https://onco.cc/technologies/fertility-preservation/>, <https://onco.cc/technologies/colposcopy-excision/>, <https://onco.cc/technologies/mri/>, <https://onco.cc/technologies/pet-ct/> ;
  onco:drugs <https://onco.cc/drugs/cisplatin/>, <https://onco.cc/drugs/carboplatin/>, <https://onco.cc/drugs/paclitaxel/>, <https://onco.cc/drugs/pembrolizumab/> ;
  onco:terms <https://onco.cc/terms/hpv-status/>, <https://onco.cc/terms/chemoradiation/>, <https://onco.cc/terms/lymphadenectomy/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-herbst-diethylstilbestrol-vaginal-adenocarcinoma-nejm-1971/>, <https://onco.cc/key-papers/paper-figo-cancer-report-cancer-of-the-vagina-ijgo-2018/> ;
  onco:pipeline <https://onco.cc/drugs/pembrolizumab/> ;
  onco:standardOfCare <https://onco.cc/technologies/histopathology-ihc/>, <https://onco.cc/technologies/mri/>, <https://onco.cc/technologies/pet-ct/>, <https://onco.cc/terms/lymphadenectomy/>, <https://onco.cc/technologies/fertility-preservation/>, <https://onco.cc/technologies/imrt-igrt/>, <https://onco.cc/technologies/imrt-igrt/>, <https://onco.cc/technologies/brachytherapy/>, <https://onco.cc/drugs/cisplatin/>, <https://onco.cc/terms/chemoradiation/>, <https://onco.cc/drugs/carboplatin/>, <https://onco.cc/drugs/paclitaxel/>, <https://onco.cc/drugs/pembrolizumab/>, <https://onco.cc/technologies/colposcopy-excision/> .