# OnCo record vaginal-squamous-cell-carcinoma (cancer). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/cancers/vaginal-squamous-cell-carcinoma/>
  a schema:MedicalCondition ;
  onco:kind "cancer" ;
  schema:identifier "vaginal-squamous-cell-carcinoma" ;
  schema:name "Vaginal squamous cell carcinoma (HPV-associated)"@en ;
  schema:alternateName "Primary vaginal squamous cell carcinoma"@en, "HPV-related vaginal cancer"@en, "Vaginal cancer treated with chemoradiotherapy"@en, "VAIN and vaginal squamous carcinoma"@en ;
  schema:description "Vaginal squamous cell carcinoma is the commonest form of vaginal cancer, caused by the same HPV infection as cervical cancer and often following earlier cervical disease. It is treated much as cervical cancer is, with radiotherapy, brachytherapy and cisplatin for most stages and surgery only for small upper-vaginal tumours, and it is prevented by HPV vaccination and cervical screening."@en ;
  schema:url <https://onco.cc/cancers/vaginal-squamous-cell-carcinoma/> ;
  schema:dateModified "2026-09-18"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Vaginal_cancer> ;
  schema:citation <https://www.nccn.org/guidelines/guidelines-detail?category=1&id=1481>, <https://en.wikipedia.org/wiki/Vaginal_cancer> ;
  onco:tag "subtype-page", "gynaecologic" ;
  onco:related <https://onco.cc/cancers/vaginal-adenocarcinoma/>, <https://onco.cc/cancers/vaginal/>, <https://onco.cc/cancers/locally-advanced-cervical-cancer/>, <https://onco.cc/cancers/hpv-associated-vulvar-cancer/> ;
  onco:technologies <https://onco.cc/technologies/brachytherapy/>, <https://onco.cc/technologies/imrt-igrt/>, <https://onco.cc/technologies/checkpoint-inhibitor/>, <https://onco.cc/technologies/hpv-vaccine/>, <https://onco.cc/technologies/hpv-testing/>, <https://onco.cc/technologies/colposcopy-excision/>, <https://onco.cc/technologies/precancer-ablation/> ;
  onco:targets <https://onco.cc/targets/pd1/>, <https://onco.cc/targets/pdl1/> ;
  onco:drugs <https://onco.cc/drugs/cisplatin/>, <https://onco.cc/drugs/carboplatin/>, <https://onco.cc/drugs/paclitaxel/>, <https://onco.cc/drugs/pembrolizumab/>, <https://onco.cc/drugs/fluorouracil/>, <https://onco.cc/drugs/gardasil-9/> ;
  onco:terms <https://onco.cc/terms/hpv-p16/>, <https://onco.cc/terms/hpv-status/>, <https://onco.cc/terms/chemoradiation/>, <https://onco.cc/terms/cin-hsil/>, <https://onco.cc/terms/lymphadenectomy/> ;
  onco:trials <https://onco.cc/trials/nct04422366/>, <https://onco.cc/trials/nct05027776/>, <https://onco.cc/trials/nct07572396/>, <https://onco.cc/trials/keynote-826/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-figo-cancer-report-cancer-of-the-vagina-ijgo-2018/>, <https://onco.cc/key-papers/paper-figo-annual-report-carcinoma-of-the-vagina-ijgo-2006/> ;
  onco:pipeline <https://onco.cc/drugs/pembrolizumab/>, <https://onco.cc/technologies/hpv-vaccine/>, <https://onco.cc/trials/nct07572396/> ;
  onco:standardOfCare <https://onco.cc/technologies/colposcopy-excision/>, <https://onco.cc/technologies/precancer-ablation/>, <https://onco.cc/drugs/fluorouracil/>, <https://onco.cc/technologies/brachytherapy/>, <https://onco.cc/technologies/hpv-vaccine/>, <https://onco.cc/drugs/gardasil-9/>, <https://onco.cc/trials/nct04422366/>, <https://onco.cc/trials/nct05027776/>, <https://onco.cc/technologies/brachytherapy/>, <https://onco.cc/terms/lymphadenectomy/>, <https://onco.cc/technologies/imrt-igrt/>, <https://onco.cc/technologies/brachytherapy/>, <https://onco.cc/drugs/cisplatin/>, <https://onco.cc/terms/chemoradiation/>, <https://onco.cc/drugs/carboplatin/>, <https://onco.cc/drugs/paclitaxel/>, <https://onco.cc/drugs/pembrolizumab/>, <https://onco.cc/trials/keynote-826/> .