# OnCo record vandetanib (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/vandetanib/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "vandetanib" ;
  schema:name "Vandetanib"@en ;
  schema:description "Vandetanib was the first drug approved for medullary thyroid cancer (2011), now largely replaced by RET-selective selpercatinib."@en ;
  schema:url <https://onco.cc/drugs/vandetanib/> ;
  schema:dateModified "2026-09-07"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Vandetanib> ;
  owl:sameAs <http://www.wikidata.org/entity/Q7914515> ;
  schema:citation <https://dailymed.nlm.nih.gov/dailymed/search.cfm?query=Vandetanib> ;
  onco:status "approved" ;
  onco:modality "Small-molecule kinase inhibitor (RET, VEGFR, EGFR)" ;
  schema:alternateName "Caprelsa" ;
  onco:approval "US 2011: Symptomatic or progressive medullary thyroid cancer" ;
  onco:cancers <https://onco.cc/cancers/thyroid/>, <https://onco.cc/cancers/medullary-thyroid-cancer/> ;
  onco:technologies <https://onco.cc/technologies/kinase-inhibitors/> ;
  onco:targets <https://onco.cc/targets/ret/>, <https://onco.cc/targets/vegf/>, <https://onco.cc/targets/egfr/> ;
  onco:companies <https://onco.cc/companies/sanofi/> ;
  onco:trials <https://onco.cc/trials/libretto-531/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-zeta-vandetanib-mtc-wells-jco-2012/> .