# OnCo record venetoclax-plus-hma (pairing). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/pairings/venetoclax-plus-hma/>
  a schema:MedicalTherapy ;
  onco:kind "pairing" ;
  schema:identifier "venetoclax-plus-hma" ;
  schema:name "Venetoclax + hypomethylating agent"@en ;
  schema:description "Azacitidine primes leukaemia cells for death; venetoclax removes the BCL-2 shield. Together they roughly doubled remissions in older AML."@en ;
  schema:url <https://onco.cc/pairings/venetoclax-plus-hma/> ;
  schema:dateModified "2026-09-07"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT02993523>, <https://clinicaltrials.gov/study/NCT04657081> ;
  onco:cancers <https://onco.cc/cancers/aml/> ;
  onco:drugs <https://onco.cc/drugs/venetoclax/>, <https://onco.cc/drugs/azacitidine/>, <https://onco.cc/drugs/decitabine-cedazuridine/> ;
  onco:pathways <https://onco.cc/pathways/apoptosis-bcl2/> ;
  onco:trials <https://onco.cc/trials/viale-a/>, <https://onco.cc/trials/ascertain-v/> ;
  onco:pairs <https://onco.cc/drugs/venetoclax/>, <https://onco.cc/drugs/azacitidine/> .