# OnCo record ventana-cldn18-43-14a (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/ventana-cldn18-43-14a/>
  a schema:MedicalTest ;
  onco:kind "drug" ;
  schema:identifier "ventana-cldn18-43-14a" ;
  schema:name "VENTANA CLDN18 (43-14A) RxDx Assay"@en ;
  schema:description "The stain that decides whether stomach or junction cancer is claudin 18.2-positive and so eligible for zolbetuximab."@en ;
  schema:url <https://onco.cc/drugs/ventana-cldn18-43-14a/> ;
  schema:dateModified "2026-11-03"^^xsd:date ;
  schema:citation <https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfpma/pma.cfm?id=P230018>, <https://www.fda.gov/medical-devices/in-vitro-diagnostics/list-cleared-or-approved-companion-diagnostic-devices-in-vitro-and-imaging-tools> ;
  onco:status "approved" ;
  onco:tag "test" ;
  onco:modality "Immunohistochemistry companion diagnostic assay (claudin 18 protein, gastric tumour tissue)" ;
  schema:alternateName "VENTANA CLDN18 (43-14A) RxDx Assay" ;
  onco:approval "US 2024: Companion diagnostic for zolbetuximab in gastric or GEJ adenocarcinoma (claudin 18 in at least 75% of viable tumour cells)" ;
  onco:related <https://onco.cc/biomarkers/cldn18-2-expression/> ;
  onco:cancers <https://onco.cc/cancers/gastric/> ;
  onco:technologies <https://onco.cc/technologies/companion-diagnostic/>, <https://onco.cc/technologies/histopathology-ihc/> ;
  onco:targets <https://onco.cc/targets/cldn18-2/> ;
  onco:drugs <https://onco.cc/drugs/zolbetuximab/> ;
  onco:companies <https://onco.cc/companies/roche-genentech/> ;
  onco:terms <https://onco.cc/terms/ihc/>, <https://onco.cc/terms/companion-diagnostic-term/> .