# OnCo record ventana-mmr-rxdx (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/ventana-mmr-rxdx/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "ventana-mmr-rxdx" ;
  schema:name "VENTANA MMR RxDx Panel"@en ;
  schema:description "A four-stain test that shows whether a womb cancer has lost its DNA spell-checker, which makes immunotherapy likely to work."@en ;
  schema:url <https://onco.cc/drugs/ventana-mmr-rxdx/> ;
  schema:dateModified "2026-09-10"^^xsd:date ;
  schema:citation <https://web.archive.org/web/20260217063458/https://www.fda.gov/drugs/resources-information-approved-drugs/fda-grants-accelerated-approval-dostarlimab-gxly-dmmr-endometrial-cancer> ;
  onco:status "approved" ;
  onco:tag "test" ;
  onco:modality "Mismatch-repair immunohistochemistry companion diagnostic assay" ;
  schema:alternateName "VENTANA MMR RxDx" ;
  onco:approval "US 2021: Companion diagnostic for dostarlimab in dMMR endometrial cancer" ;
  onco:cancers <https://onco.cc/cancers/endometrial/>, <https://onco.cc/cancers/colorectal/>, <https://onco.cc/cancers/pancreatic/> ;
  onco:technologies <https://onco.cc/technologies/msi-mmr-testing/>, <https://onco.cc/technologies/companion-diagnostic/>, <https://onco.cc/technologies/histopathology-ihc/> ;
  onco:drugs <https://onco.cc/drugs/dostarlimab/>, <https://onco.cc/drugs/pembrolizumab/> ;
  onco:companies <https://onco.cc/companies/roche-genentech/> ;
  onco:terms <https://onco.cc/terms/msi/>, <https://onco.cc/terms/mss-pmmr/>, <https://onco.cc/terms/lynch-syndrome/>, <https://onco.cc/terms/endometrial-molecular-classes/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-luchini-msi-dmmr-pancreatic-systematic-review-gut-2021/>, <https://onco.cc/key-papers/paper-moreira-lynch-syndrome-identification-jama-2012/>, <https://onco.cc/key-papers/paper-sepulveda-molecular-biomarkers-colorectal-guideline-jco-2017/> .