# OnCo record vincristine (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix owl: <http://www.w3.org/2002/07/owl#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/vincristine/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "vincristine" ;
  schema:name "Vincristine"@en ;
  schema:description "A plant-derived chemotherapy from the Madagascar periwinkle that has been in almost every childhood leukaemia and lymphoma regimen since the 1960s."@en ;
  schema:url <https://onco.cc/drugs/vincristine/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Vincristine> ;
  owl:sameAs <http://www.wikidata.org/entity/Q408977> ;
  schema:citation <https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=vincristine> ;
  onco:status "approved" ;
  onco:tag "gap-fill", "generic", "who-essential" ;
  onco:modality "Vinca alkaloid (microtubule inhibitor)" ;
  schema:alternateName "Oncovin / Marqibo" ;
  onco:approval "US 1963: Acute leukaemia; Hodgkin and non-Hodgkin lymphoma, rhabdomyosarcoma, neuroblastoma, Wilms tumour" ;
  onco:acceleratedApproval "US 2012-08-09: Adults with Philadelphia (PH) chromosome negative (-) ALL in second relapse or greater relapsed or whose disease has progressed following 2 or greater treatment lines of anti-leukemia therapies" ;
  onco:cancers <https://onco.cc/cancers/all-leukemia/>, <https://onco.cc/cancers/dlbcl/>, <https://onco.cc/cancers/hodgkin-lymphoma/>, <https://onco.cc/cancers/rhabdomyosarcoma/>, <https://onco.cc/cancers/ewing-sarcoma/>, <https://onco.cc/cancers/wilms-tumor/>, <https://onco.cc/cancers/neuroblastoma/>, <https://onco.cc/cancers/medulloblastoma/>, <https://onco.cc/cancers/retinoblastoma/>, <https://onco.cc/cancers/oligodendroglioma/> ;
  onco:technologies <https://onco.cc/technologies/cytotoxic-chemotherapy/> ;
  onco:companies <https://onco.cc/companies/eli-lilly/> ;
  onco:trials <https://onco.cc/trials/rtog-9402/>, <https://onco.cc/trials/eortc-26951/>, <https://onco.cc/trials/nct06097364/>, <https://onco.cc/trials/nct04529772/>, <https://onco.cc/trials/nct06717347/>, <https://onco.cc/trials/nct06191744/>, <https://onco.cc/trials/nct06911502/>, <https://onco.cc/trials/nct06091865/>, <https://onco.cc/trials/nct06091254/>, <https://onco.cc/trials/nct05888493/>, <https://onco.cc/trials/nct03407144/>, <https://onco.cc/trials/nct04663347/>, <https://onco.cc/trials/nct04542824/>, <https://onco.cc/trials/nct05201248/>, <https://onco.cc/trials/nct07730515/>, <https://onco.cc/trials/nct06564038/>, <https://onco.cc/trials/nct04623541/>, <https://onco.cc/trials/nct04980222/>, <https://onco.cc/trials/nct07387926/>, <https://onco.cc/trials/nct06947967/>, <https://onco.cc/trials/nct06425302/> .