# OnCo record vysis-alk-break-apart-fish (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/vysis-alk-break-apart-fish/>
  a schema:MedicalTest ;
  onco:kind "drug" ;
  schema:identifier "vysis-alk-break-apart-fish" ;
  schema:name "Vysis ALK Break Apart FISH Probe Kit"@en ;
  schema:description "The test approved with crizotinib in 2011 to find ALK-rearranged lung cancer, still listed as companion to brigatinib and ensartinib."@en ;
  schema:url <https://onco.cc/drugs/vysis-alk-break-apart-fish/> ;
  schema:dateModified "2026-11-03"^^xsd:date ;
  schema:citation <https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfpma/pma.cfm?id=P110012>, <https://www.fda.gov/medical-devices/in-vitro-diagnostics/list-cleared-or-approved-companion-diagnostic-devices-in-vitro-and-imaging-tools> ;
  onco:status "approved" ;
  onco:tag "test" ;
  onco:modality "FISH companion diagnostic test (ALK rearrangement, lung tumour tissue)" ;
  schema:alternateName "Vysis ALK Break Apart FISH Probe Kit" ;
  onco:approval "US 2011: Companion diagnostic for crizotinib in ALK-rearranged NSCLC", "US 2020: Companion diagnostic for brigatinib", "US 2025: Companion diagnostic for ensartinib" ;
  onco:related <https://onco.cc/drugs/ventana-alk-d5f3-cdx/>, <https://onco.cc/biomarkers/alk-fusion/> ;
  onco:cancers <https://onco.cc/cancers/nsclc/> ;
  onco:technologies <https://onco.cc/technologies/companion-diagnostic/>, <https://onco.cc/technologies/cytogenetics-fish/> ;
  onco:targets <https://onco.cc/targets/alk/> ;
  onco:drugs <https://onco.cc/drugs/crizotinib/>, <https://onco.cc/drugs/brigatinib/>, <https://onco.cc/drugs/ensartinib/> ;
  onco:companies <https://onco.cc/companies/abbott/> ;
  onco:terms <https://onco.cc/terms/fish/>, <https://onco.cc/terms/companion-diagnostic-term/> .