# OnCo record whole-genome-doubling (term). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/terms/whole-genome-doubling/>
  a schema:DefinedTerm ;
  onco:kind "term" ;
  schema:identifier "whole-genome-doubling" ;
  schema:name "Whole-genome doubling (WGD)"@en ;
  schema:description "Whole-genome doubling is a single event in which a cancer cell duplicates its entire genome, becoming tetraploid. It happens in about a third of cancers and buffers the chaos that follows."@en ;
  schema:url <https://onco.cc/terms/whole-genome-doubling/> ;
  schema:dateModified "2026-09-08"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Polyploidy> ;
  schema:citation <https://doi.org/10.1038/s41588-018-0165-1> ;
  onco:targets <https://onco.cc/targets/tp53/> ;
  onco:pathways <https://onco.cc/pathways/chromosomal-instability/>, <https://onco.cc/pathways/p53-cell-cycle/> ;
  onco:terms <https://onco.cc/terms/genome-instability-mutation/> ;
  onco:keyPapers <https://onco.cc/key-papers/paper-bielski-nat-genet/> .