# OnCo record xdh (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/xdh/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "xdh" ;
  schema:name "Xanthine oxidase (XDH)"@en ;
  schema:description "Xanthine oxidase makes uric acid from the breakdown of DNA; allopurinol blocks it to prevent the kidney damage of tumour lysis syndrome when chemotherapy kills many cancer cells at once."@en ;
  schema:url <https://onco.cc/targets/xdh/> ;
  schema:dateModified "2026-09-04"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Xanthine_oxidase>, <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:12805>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000158125>, <https://www.uniprot.org/uniprotkb/P47989/entry>, <https://www.ncbi.nlm.nih.gov/gene/7498> ;
  schema:citation <https://www.uniprot.org/uniprotkb/P47989/entry>, <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:12805>, <https://www.ebi.ac.uk/chembl/explore/target/CHEMBL1929> ;
  onco:tag "chembl-gap" ;
  schema:alternateName "XDH" ;
  onco:targetClass "enzyme" ;
  onco:firstDescribed "1993"^^xsd:gYear ;
  onco:cancers <https://onco.cc/cancers/all-leukemia/>, <https://onco.cc/cancers/aml/>, <https://onco.cc/cancers/burkitt-lymphoma/>, <https://onco.cc/cancers/dlbcl/> ;
  onco:drugs <https://onco.cc/drugs/rasburicase/> ;
  onco:terms <https://onco.cc/terms/tumor-lysis-syndrome/> .