# OnCo record xevinapant (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/xevinapant/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "xevinapant" ;
  schema:name "Xevinapant"@en ;
  schema:alternateName "Debio 1143"@en, "AT-406"@en, "SM-406"@en ;
  schema:description "Xevinapant was a tablet meant to make head and neck cancer cells easier to kill with chemoradiation by removing the proteins that stop them dying. A promising mid-stage trial was followed by a phase 3 that was stopped in 2024 because it was not working."@en ;
  schema:url <https://onco.cc/drugs/xevinapant/> ;
  schema:dateModified "2026-09-17"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Xevinapant> ;
  schema:citation <https://en.wikipedia.org/wiki/Xevinapant> ;
  onco:status "negative" ;
  onco:tag "subtype-drugs-wave" ;
  onco:modality "Oral IAP antagonist (SMAC mimetic) radiosensitiser" ;
  onco:related <https://onco.cc/drugs/cisplatin/> ;
  onco:cancers <https://onco.cc/cancers/hpv-negative-head-and-neck-cancer/> ;
  onco:technologies <https://onco.cc/technologies/radiosensitisers/> ;
  onco:companies <https://onco.cc/companies/debiopharm/>, <https://onco.cc/companies/merck-kgaa/> .