# OnCo record xpo1 (target). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/targets/xpo1/>
  a schema:BioChemEntity ;
  onco:kind "target" ;
  schema:identifier "xpo1" ;
  schema:name "Exportin-1 (XPO1)"@en ;
  schema:description "The export pump that carries tumour suppressor proteins such as p53 out of the nucleus, where they cannot act. Selinexor blocks it so those brakes stay in the nucleus and cancer cells die."@en ;
  schema:url <https://onco.cc/targets/xpo1/> ;
  schema:dateModified "2026-09-04"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/XPO1>, <https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/HGNC:12825>, <https://www.ensembl.org/Homo_sapiens/Gene/Summary?g=ENSG00000082898>, <https://www.uniprot.org/uniprotkb/O14980/entry>, <https://www.ncbi.nlm.nih.gov/gene/7514> ;
  schema:citation <https://www.uniprot.org/uniprotkb/O14980/entry> ;
  schema:alternateName "XPO1" ;
  onco:targetClass "other" ;
  onco:firstDescribed "1997"^^xsd:gYear ;
  onco:cancers <https://onco.cc/cancers/multiple-myeloma/>, <https://onco.cc/cancers/dlbcl/>, <https://onco.cc/cancers/endometrial/> ;
  onco:drugs <https://onco.cc/drugs/selinexor/> .