# OnCo record zanidatamab-zovodotin (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/zanidatamab-zovodotin/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "zanidatamab-zovodotin" ;
  schema:name "Zanidatamab zovodotin"@en ;
  schema:alternateName "ZW49"@en ;
  schema:description "Zanidatamab zovodotin joined the two-armed HER2 antibody zanidatamab to a cell-killing payload. It was tested in early trials in HER2-expressing cancers; the plain antibody went on to approval, the conjugate did not progress beyond phase 1."@en ;
  schema:url <https://onco.cc/drugs/zanidatamab-zovodotin/> ;
  schema:dateModified "2026-09-17"^^xsd:date ;
  onco:status "phase-1" ;
  onco:tag "subtype-drugs-wave" ;
  onco:modality "Biparatopic HER2 antibody-drug conjugate" ;
  onco:related <https://onco.cc/drugs/zanidatamab/>, <https://onco.cc/drugs/trastuzumab-deruxtecan/> ;
  onco:cancers <https://onco.cc/cancers/breast-her2-positive/> ;
  onco:technologies <https://onco.cc/technologies/adc/> ;
  onco:targets <https://onco.cc/targets/her2/> ;
  onco:companies <https://onco.cc/companies/zymeworks/> .