# OnCo record zen-3694-abemaciclib-nut (trial). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/trials/zen-3694-abemaciclib-nut/>
  a schema:MedicalTrial ;
  onco:kind "trial" ;
  schema:identifier "zen-3694-abemaciclib-nut", "NCT05372640" ;
  schema:name "ZEN-3694 with abemaciclib in NUT carcinoma, breast cancer and other solid tumours (NCI phase 1)"@en ;
  schema:description "A chemotherapy-free combination for NUT carcinoma: a BET inhibitor with a CDK4/6 inhibitor, on the reasoning that both act on the MYC-driven growth programme the fusion switches on."@en ;
  schema:url <https://onco.cc/trials/zen-3694-abemaciclib-nut/> ;
  schema:dateModified "2026-09-16"^^xsd:date ;
  schema:citation <https://clinicaltrials.gov/study/NCT05372640> ;
  onco:status "recruiting" ;
  onco:tag "owner-request" ;
  onco:phase "1" ;
  schema:startDate "2023-08-10" ;
  onco:cancers <https://onco.cc/cancers/nut-carcinoma/> ;
  onco:technologies <https://onco.cc/technologies/epigenetic-drugs/> ;
  onco:targets <https://onco.cc/targets/cdk4-6/> ;
  onco:drugs <https://onco.cc/drugs/zen-3694/>, <https://onco.cc/drugs/abemaciclib/> ;
  onco:institutions <https://onco.cc/institutions/nci/> .