# OnCo record zibotentan (drug). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/drugs/zibotentan/>
  a schema:Drug ;
  onco:kind "drug" ;
  schema:identifier "zibotentan" ;
  schema:name "Zibotentan"@en ;
  schema:alternateName "ZD4054"@en ;
  schema:description "A drug blocking a signal that prostate cancer uses to grow in bone. Three trials in prostate cancer found no survival benefit and it was dropped."@en ;
  schema:url <https://onco.cc/drugs/zibotentan/> ;
  schema:dateModified "2026-09-25"^^xsd:date ;
  schema:citation <https://doi.org/10.1002/cncr.27674> ;
  onco:status "withdrawn" ;
  onco:modality "small molecule" ;
  onco:cancers <https://onco.cc/cancers/prostate/>, <https://onco.cc/cancers/prostate-mcrpc/> ;
  onco:targets <https://onco.cc/targets/ednra/> ;
  onco:companies <https://onco.cc/companies/astrazeneca/> ;
  onco:terms <https://onco.cc/terms/bone-metastases/>, <https://onco.cc/terms/castration-resistance/> ;
  onco:trials <https://onco.cc/trials/enthuse-m1-zibotentan/>, <https://onco.cc/trials/swog-s0421-atrasentan/> .