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GIST was the first solid tumour cured-in-practice by a targeted pill; synovial sarcoma got the first TCR-T therapy."},{"label":"Osteosarcoma","href":"/cancers/osteosarcoma/","tip":"Osteosarcoma is the most common bone cancer, mostly in teenagers. Chemotherapy plus surgery cures about two-thirds when it has not spread; because no new drug has beaten that chemotherapy in a large trial in 30 years, the next gains are being sought in cellular therapy against GD2, HER2 and B7-H3."}],"tags":[{"label":"patient","href":"/tagged/patient/","tip":"Every record tagged patient."},{"label":"technology","href":"/tagged/technology/","tip":"Every record tagged technology."}]},"sortKeys":{"year":0}},{"id":"sidney-farber","name":"Sidney Farber","tldr":"In 1947-48 he showed that the folate antagonist aminopterin could send childhood leukaemia into remission, the first drug ever to do so. 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