{"slug":"antibody-target","tag":"antibody-target","variants":["antibody-target"],"description":"No description yet","count":3,"kinds":{"target":3},"related":[{"slug":"car-t-target","tag":"car-t-target","shared":1}],"records":[{"id":"gd2","kind":"target","name":"GD2 (disialoganglioside)","route":"/targets/gd2/","tldr":"GD2 is a sugar-fat molecule on the surface of neuroblastoma cells (and some other childhood and adult tumours) with almost none on normal tissue except nerves, which is why anti-GD2 drugs cause pain."},{"id":"cd20","kind":"target","name":"CD20","route":"/targets/cd20/","tldr":"CD20 is a B-cell marker; rituximab against it was the first antibody approved for cancer, in 1997."},{"id":"cd38","kind":"target","name":"CD38","route":"/targets/cd38/","tldr":"CD38 is a myeloma surface enzyme and the target of daratumumab, which is now given as a quick under-the-skin injection."}]}