{"slug":"cervical","tag":"cervical","variants":["cervical"],"description":"No description yet","count":9,"kinds":{"person":9},"related":[{"slug":"cooperative-group","tag":"cooperative-group","shared":3},{"slug":"immunotherapy","tag":"immunotherapy","shared":2},{"slug":"ovarian","tag":"ovarian","shared":2},{"slug":"surgery","tag":"surgery","shared":2},{"slug":"trialist","tag":"trialist","shared":2},{"slug":"adc","tag":"adc","shared":1},{"slug":"australia","tag":"australia","shared":1},{"slug":"chemoradiotherapy","tag":"chemoradiotherapy","shared":1},{"slug":"de-escalation","tag":"de-escalation","shared":1},{"slug":"global-health","tag":"global health","shared":1},{"slug":"guidelines","tag":"guidelines","shared":1},{"slug":"gynaecological","tag":"gynaecological","shared":1}],"records":[{"id":"ignace-vergote","kind":"person","name":"Ignace Vergote","route":"/people/ignace-vergote/","tldr":"Led the EORTC trial that made neoadjuvant chemotherapy acceptable in ovarian cancer and innovaTV 301, the first ADC survival win in cervical cancer."},{"id":"domenica-lorusso","kind":"person","name":"Domenica Lorusso","route":"/people/domenica-lorusso/","tldr":"Led KEYNOTE-A18, which showed adding pembrolizumab to chemoradiotherapy improves survival in locally advanced cervical cancer."},{"id":"nicoletta-colombo","kind":"person","name":"Nicoletta Colombo","route":"/people/nicoletta-colombo/","tldr":"Led KEYNOTE-826, which made pembrolizumab plus chemotherapy the first-line standard for recurrent or metastatic cervical cancer."},{"id":"bradley-monk","kind":"person","name":"Bradley J. Monk","route":"/people/bradley-monk/","tldr":"Gynaecologic oncologist who co-led KEYNOTE-826, innovaTV 301 and KEYNOTE-A18, the trials that rebuilt cervical cancer treatment."},{"id":"pedro-ramirez","kind":"person","name":"Pedro T. Ramirez","route":"/people/pedro-ramirez/","tldr":"Surgeon who led the LACC trial, which unexpectedly showed keyhole hysterectomy worsens survival in early cervical cancer."},{"id":"mary-mccormack","kind":"person","name":"Mary McCormack","route":"/people/mary-mccormack/","tldr":"Led INTERLACE, which showed a short course of chemotherapy before chemoradiation cuts cervical cancer deaths using cheap, available drugs."},{"id":"linda-mileshkin","kind":"person","name":"Linda Mileshkin","route":"/people/linda-mileshkin/","tldr":"Led OUTBACK, which showed adding chemotherapy after chemoradiation does not help cervical cancer, a key negative result."},{"id":"krishnansu-tewari","kind":"person","name":"Krishnansu S. Tewari","route":"/people/krishnansu-tewari/","tldr":"California gynaecologic oncologist who led GOG 240, the trial that made bevacizumab the first targeted drug to lengthen survival in advanced cervical cancer, and EMPOWER-Cervical 1, which did the same for the PD-1 antibody cemiplimab."},{"id":"marie-plante","kind":"person","name":"Marie Plante","route":"/people/marie-plante/","tldr":"Quebec surgeon who pioneered fertility-sparing surgery for cervical cancer and led SHAPE, the trial that showed a simple hysterectomy is enough for low-risk early cervical cancer."}]}