{"slug":"cognition","tag":"cognition","variants":["cognition"],"description":"No description yet","count":3,"kinds":{"technology":2,"bottleneck":1},"related":[{"slug":"rejuvenation","tag":"rejuvenation","shared":3},{"slug":"survivorship","tag":"survivorship","shared":3},{"slug":"cell-therapy","tag":"cell-therapy","shared":1},{"slug":"instruments","tag":"instruments","shared":1},{"slug":"measurement","tag":"measurement","shared":1},{"slug":"open-problem","tag":"open-problem","shared":1},{"slug":"transplant","tag":"transplant","shared":1}],"records":[{"id":"rejuv-tx-icans-and-neurocognition","kind":"technology","name":"ICANS, and whether thinking recovers after CAR-T","route":"/technologies/rejuv-tx-icans-and-neurocognition/","status":"established","tldr":"CAR-T can cause a short-lived brain disturbance in the first weeks: confusion, trouble finding words, tremor, sometimes seizures. It almost always resolves. Afterwards, measured outcomes for most people are close to the general population, while a substantial minority report trouble with memory or concentration."},{"id":"rejuv-agenda-nothing-restores-cognition","kind":"bottleneck","name":"No treatment restores the thinking that cancer treatment takes","route":"/bottlenecks/rejuv-agenda-nothing-restores-cognition/","tldr":"The memory and concentration problems after chemotherapy and cranial radiotherapy are real and measurable. Every drug tested against them has failed, including one tested properly in 276 people, and nothing restores lost processing speed."},{"id":"rejuv-measure-cognitive-function","kind":"technology","name":"Measuring memory and concentration after treatment","route":"/technologies/rejuv-measure-cognitive-function/","status":"established","tldr":"What a person notices about their own memory and what a formal test measures are two different things, and they agree only weakly. The questionnaire most used for the first is FACT-Cog; the tests used for the second were standardised by an international task force so that studies could be compared."}]}