{"slug":"egfr-inhibitor","tag":"egfr-inhibitor","variants":["egfr-inhibitor"],"description":"No description yet","count":1,"kinds":{"protocol":1},"related":[{"slug":"protocol","tag":"protocol","shared":1},{"slug":"skin-toxicity","tag":"skin-toxicity","shared":1},{"slug":"supportive-care","tag":"supportive-care","shared":1}],"records":[{"id":"egfr-inhibitor-rash-prophylaxis","kind":"protocol","name":"EGFR inhibitor rash: pre-emptive skin care, antibiotics and dose changes","route":"/protocols/egfr-inhibitor-rash-prophylaxis/","tldr":"Drugs that block EGFR, such as cetuximab, panitumumab, amivantamab and EGFR tablets for lung cancer, very often cause an acne-like rash. Starting skin care on day one makes a bad rash much less likely: doxycycline or minocycline for the first weeks, moisturiser, sunscreen, and sometimes a mild steroid cream. Tell your team early if it spreads or hurts: a pause or lower dose may help."}]}