{"slug":"hpv","tag":"hpv","variants":["hpv"],"description":"No description yet","count":8,"kinds":{"person":4,"cancer":4},"related":[{"slug":"epidemiology","tag":"epidemiology","shared":2},{"slug":"gynaecologic","tag":"gynaecologic","shared":2},{"slug":"prevention","tag":"prevention","shared":2},{"slug":"rare","tag":"rare","shared":2},{"slug":"screening","tag":"screening","shared":2},{"slug":"de-escalation","tag":"de-escalation","shared":1},{"slug":"gastrointestinal","tag":"gastrointestinal","shared":1},{"slug":"genitourinary","tag":"genitourinary","shared":1},{"slug":"head-and-neck","tag":"head-and-neck","shared":1},{"slug":"latin-america","tag":"latin-america","shared":1}],"records":[{"id":"maura-gillison","kind":"person","name":"Maura L. Gillison","route":"/people/maura-gillison/","tldr":"Established that HPV causes a distinct, better-prognosis form of throat cancer and led RTOG 1016 on how to treat it."},{"id":"peter-sasieni","kind":"person","name":"Peter Sasieni","route":"/people/peter-sasieni/","tldr":"Epidemiologist who showed HPV vaccination has nearly eliminated cervical cancer in vaccinated English women and leads NHS-Galleri."},{"id":"nubia-munoz","kind":"person","name":"Nubia Muñoz","route":"/people/nubia-munoz/","tldr":"Colombian epidemiologist whose IARC studies proved HPV causes cervical cancer and identified the types the vaccines target."},{"id":"mark-schiffman","kind":"person","name":"Mark Schiffman","route":"/people/mark-schiffman/","tldr":"NCI epidemiologist whose HPV natural history studies underpin HPV-based cervical screening and risk-based management worldwide."},{"id":"anal","kind":"cancer","name":"Anal cancer (squamous cell carcinoma)","route":"/cancers/anal/","tldr":"An HPV-caused cancer of the anal canal that is usually cured without surgery by combined chemotherapy and radiation. Prevention (HPV vaccination, screening of high-risk groups) and immunotherapy for advanced disease are the new fronts."},{"id":"vulvar","kind":"cancer","name":"Vulvar cancer","route":"/cancers/vulvar/","tldr":"An uncommon cancer of the external genitalia with two distinct causes: HPV infection in younger women and chronic skin inflammation in older women. Surgery is the mainstay, and sentinel-node biopsy has made it far less mutilating."},{"id":"penile","kind":"cancer","name":"Penile cancer","route":"/cancers/penile/","tldr":"Penile cancer is a squamous skin-type cancer, about half of it caused by HPV. Caught early it is usually cured with organ-sparing surgery that has replaced amputation, and HPV vaccination and circumcision prevent it; the hard cases are those with lymph-node spread, where cisplatin-based chemotherapy plus surgery and now immunotherapy are being tested in the InPACT trial."},{"id":"vaginal","kind":"cancer","name":"Vaginal cancer","route":"/cancers/vaginal/","tldr":"Primary vaginal cancer is rare and mostly caused by HPV, the virus behind cervical cancer. It is treated like cervical cancer, with weekly cisplatin alongside external and internal radiotherapy, which controls most tumours while preserving the organ; HPV vaccination and cervical screening, which also detects vaginal precursors, are steadily reducing it."}]}