{"slug":"liquid-biopsy","tag":"liquid-biopsy","variants":["liquid-biopsy"],"description":"No description yet","count":5,"kinds":{"section":1,"person":3,"roadmap":1},"related":[{"slug":"ctdna","tag":"ctdna","shared":2},{"slug":"genomics","tag":"genomics","shared":2},{"slug":"mced","tag":"mced","shared":2},{"slug":"breast","tag":"breast","shared":1},{"slug":"early-detection","tag":"early-detection","shared":1},{"slug":"mrd","tag":"mrd","shared":1},{"slug":"pathology","tag":"pathology","shared":1}],"records":[{"id":"diagnostics","kind":"section","name":"Diagnostics & Biomarkers","route":"/fronts/diagnostics/","tldr":"Tests on tissue and blood that say what kind of cancer it is, what is driving it, and which drugs might work."},{"id":"massimo-cristofanilli","kind":"person","name":"Massimo Cristofanilli","route":"/people/massimo-cristofanilli/","tldr":"Showed that counting tumour cells in blood predicts survival in breast cancer and co-led PALOMA-3, which brought palbociclib to endocrine-resistant disease."},{"id":"nickolas-papadopoulos","kind":"person","name":"Nickolas Papadopoulos","route":"/people/nickolas-papadopoulos/","tldr":"Co-developed CancerSEEK, the blood test that showed multi-cancer early detection is possible, and ran the first prospective screening study of it."},{"id":"nitzan-rosenfeld","kind":"person","name":"Nitzan Rosenfeld","route":"/people/nitzan-rosenfeld/","tldr":"Showed that whole-exome sequencing of blood can track how a cancer evolves, and co-founded Inivata."},{"id":"ctdna-tests","kind":"roadmap","name":"ctDNA tests roadmap: from a curiosity in plasma to blood tests that decide treatment","route":"/roadmaps/ctdna-tests/","tldr":"Blood carries fragments of tumour DNA. This roadmap follows the tests that read them, from the first sighting in 1948 to blood tests that now choose a drug, spare chemotherapy, or screen for many cancers at once, and it lists the readouts to watch next."}]}