{"slug":"methods","tag":"methods","variants":["methods"],"description":"No description yet","count":2,"kinds":{"bottleneck":1,"idea":1},"related":[{"slug":"open-problem","tag":"open-problem","shared":2},{"slug":"outcomes","tag":"outcomes","shared":2},{"slug":"rejuvenation","tag":"rejuvenation","shared":2},{"slug":"survivorship","tag":"survivorship","shared":2}],"records":[{"id":"rejuv-agenda-no-agreed-outcome-measures","kind":"bottleneck","name":"The field cannot pool its own studies, because it has not agreed what to measure","route":"/bottlenecks/rejuv-agenda-no-agreed-outcome-measures/","tldr":"On subject after subject here, the studies exist and cannot be combined, because each used a different definition, a different questionnaire or a different threshold. A prevalence that ranges from 0 to 84 per cent is a measurement problem, not a biological one."},{"id":"idea-rejuv-core-outcome-set-for-late-effects","kind":"idea","name":"Agree what to measure, so the next systematic review can pool rather than narrate","route":"/ideas/idea-rejuv-core-outcome-set-for-late-effects/","tldr":"A reported prevalence of 0 to 84 per cent for the same late effect is a measurement failure. Core outcome sets are cheap, need no new biology, and would unlock the studies the field has already paid for."}]}