{"slug":"mrd","tag":"mrd","variants":["mrd"],"description":"No description yet","count":5,"kinds":{"person":4,"roadmap":1},"related":[{"slug":"ctdna","tag":"ctdna","shared":2},{"slug":"all","tag":"all","shared":1},{"slug":"cll","tag":"cll","shared":1},{"slug":"cooperative-group","tag":"cooperative-group","shared":1},{"slug":"diagnostics","tag":"diagnostics","shared":1},{"slug":"liquid-biopsy","tag":"liquid-biopsy","shared":1},{"slug":"mced","tag":"mced","shared":1},{"slug":"myeloma","tag":"myeloma","shared":1},{"slug":"precursor","tag":"precursor","shared":1},{"slug":"uk","tag":"uk","shared":1}],"records":[{"id":"nicola-gokbuget","kind":"person","name":"Nicola Gökbuget","route":"/people/nicola-gokbuget/","tldr":"Leads the German GMALL group and showed blinatumomab clears residual leukaemia in adults with ALL."},{"id":"peter-hillmen","kind":"person","name":"Peter Hillmen","route":"/people/peter-hillmen/","tldr":"Led FLAIR, the UK trial showing MRD-guided ibrutinib plus venetoclax outperforms chemoimmunotherapy in CLL."},{"id":"ola-landgren","kind":"person","name":"C. Ola Landgren","route":"/people/ola-landgren/","tldr":"Showed that MGUS precedes essentially all myeloma and leads MRD-driven trials aiming for cure without transplant."},{"id":"viktor-adalsteinsson","kind":"person","name":"Viktor A. Adalsteinsson","route":"/people/viktor-adalsteinsson/","tldr":"Engineer who showed low-pass sequencing of blood can replace tumour biopsies and built ultra-sensitive MRD tests."},{"id":"ctdna-tests","kind":"roadmap","name":"ctDNA tests roadmap: from a curiosity in plasma to blood tests that decide treatment","route":"/roadmaps/ctdna-tests/","tldr":"Blood carries fragments of tumour DNA. This roadmap follows the tests that read them, from the first sighting in 1948 to blood tests that now choose a drug, spare chemotherapy, or screen for many cancers at once, and it lists the readouts to watch next."}]}