{"slug":"prevention","tag":"prevention","variants":["prevention"],"description":"No description yet","count":13,"kinds":{"section":1,"person":4,"term":2,"drug":5,"company":1},"related":[{"slug":"breast","tag":"breast","shared":2},{"slug":"epidemiology","tag":"epidemiology","shared":2},{"slug":"hpv","tag":"hpv","shared":2},{"slug":"law","tag":"law","shared":2},{"slug":"us","tag":"us","shared":2},{"slug":"cachexia","tag":"cachexia","shared":1},{"slug":"exercise","tag":"exercise","shared":1},{"slug":"latin-america","tag":"latin-america","shared":1},{"slug":"longevity","tag":"longevity","shared":1},{"slug":"microbiome","tag":"microbiome","shared":1},{"slug":"mpn","tag":"mpn","shared":1},{"slug":"nutrition","tag":"nutrition","shared":1}],"records":[{"id":"nutrition-lifestyle","kind":"section","name":"Diet, Exercise & Lifestyle","route":"/fronts/nutrition-lifestyle/","tldr":"What people eat, drink, weigh and do affects who gets cancer, how treatment goes, and who relapses. This front studies that with the rigour of a drug trial."},{"id":"jack-cuzick","kind":"person","name":"Jack Cuzick","route":"/people/jack-cuzick/","tldr":"Epidemiologist who led IBIS-I and IBIS-II, proving tamoxifen and anastrozole prevent breast cancer in high-risk women."},{"id":"peter-sasieni","kind":"person","name":"Peter Sasieni","route":"/people/peter-sasieni/","tldr":"Epidemiologist who showed HPV vaccination has nearly eliminated cervical cancer in vaccinated English women and leads NHS-Galleri."},{"id":"nubia-munoz","kind":"person","name":"Nubia Muñoz","route":"/people/nubia-munoz/","tldr":"Colombian epidemiologist whose IARC studies proved HPV causes cervical cancer and identified the types the vaccines target."},{"id":"andrea-decensi","kind":"person","name":"Andrea DeCensi","route":"/people/andrea-decensi/","tldr":"Italian oncologist who led TAM-01, the trial that showed a low dose of tamoxifen halves recurrence after non-invasive breast cancer with fewer side effects than the standard dose."},{"id":"tobacco-control-act","kind":"term","name":"Family Smoking Prevention and Tobacco Control Act 2009","route":"/terms/tobacco-control-act/","tldr":"The 2009 US law that finally gave the FDA power over tobacco products, the cause of roughly a third of cancer deaths, including authority to ban flavours, restrict marketing and set nicotine levels, though it may not ban cigarettes or nicotine outright."},{"id":"tobacco-21","kind":"term","name":"Tobacco 21","route":"/terms/tobacco-21/","tldr":"Since December 2019 it has been illegal across the United States to sell tobacco or vaping products to anyone under 21, a rule that started in one Massachusetts town and spread state by state, aimed at the years when most smokers start."},{"id":"raloxifene","kind":"drug","name":"Raloxifene","route":"/drugs/raloxifene/","status":"approved","tldr":"Raloxifene (Evista) is an osteoporosis tablet that also lowers the chance of developing invasive breast cancer in postmenopausal women at higher risk, with fewer womb-cancer problems than tamoxifen."},{"id":"aminolevulinic-acid","kind":"drug","name":"Aminolevulinic acid (topical, for photodynamic therapy)","route":"/drugs/aminolevulinic-acid/","status":"approved","tldr":"Aminolevulinic acid is painted on sun-damaged skin and then activated with a lamp, destroying actinic keratoses before they can become skin cancer; in Europe the gel is also approved for superficial basal cell carcinoma."},{"id":"hpv-bivalent-vaccine","kind":"drug","name":"HPV bivalent vaccine (types 16 and 18)","route":"/drugs/hpv-bivalent-vaccine/","status":"approved","tldr":"Cervarix is a vaccine against HPV types 16 and 18, the two types that cause most cervical cancers, authorised in the EU in 2007 and the US in 2009 after the 18,000-woman PATRICIA trial showed near-complete protection against type-specific precancer. GSK withdrew it from the US in 2016, but it remains WHO-prequalified and used in national programmes, including single-dose schedules."},{"id":"hpv-quadrivalent-vaccine","kind":"drug","name":"HPV quadrivalent vaccine (types 6, 11, 16 and 18)","route":"/drugs/hpv-quadrivalent-vaccine/","status":"approved","tldr":"Gardasil was the first HPV vaccine, licensed in 2006 to prevent cervical and other genital cancers and genital warts. It has been replaced in most countries by the nine-type version, Gardasil 9."},{"id":"scirouter","kind":"company","name":"SciRouter","route":"/companies/scirouter/","tldr":"SciRouter is a prevention-first longevity start-up founded by Ryan Bethencourt that sells plant-based daily supplements for people, dogs and cats, and frames cancer and age-related decline as engineering problems to be prevented rather than treated."},{"id":"aspirin","kind":"drug","name":"Aspirin","route":"/drugs/aspirin/","status":"established","tldr":"Aspirin is not a cancer drug but sits in cancer care in two places: low doses prevent clots in polycythaemia vera and essential thrombocythaemia, and long-term use lowers colorectal cancer in people with Lynch syndrome, while a trial in the healthy elderly found no benefit and possible harm."}]}