{"slug":"thoracic","tag":"thoracic","variants":["thoracic"],"description":"No description yet","count":7,"kinds":{"cancer":5,"person":2},"related":[{"slug":"subtype-page","tag":"subtype-page","shared":2},{"slug":"cooperative-group","tag":"cooperative-group","shared":1},{"slug":"europe","tag":"europe","shared":1},{"slug":"paediatric","tag":"paediatric","shared":1},{"slug":"rare","tag":"rare","shared":1},{"slug":"staging","tag":"staging","shared":1},{"slug":"surgery","tag":"surgery","shared":1}],"records":[{"id":"mesothelioma","kind":"cancer","name":"Mesothelioma","route":"/cancers/mesothelioma/","tldr":"An asbestos-caused cancer of the lung lining. Immunotherapy doublets replaced chemotherapy in 2020, and mesothelin CAR-T is under study."},{"id":"valerie-rusch","kind":"person","name":"Valerie W. Rusch","route":"/people/valerie-rusch/","tldr":"Thoracic surgeon who led the IASLC staging projects that define how lung cancer and mesothelioma are staged."},{"id":"rolf-stahel","kind":"person","name":"Rolf A. Stahel","route":"/people/rolf-stahel/","tldr":"Founded the European Thoracic Oncology Platform and leads the merged ETOP IBCSG academic trials foundation."},{"id":"thymic-epithelial","kind":"cancer","name":"Thymoma and thymic carcinoma","route":"/cancers/thymic-epithelial/","tldr":"Thymoma and thymic carcinoma are rare tumours of the thymus gland in the chest. Thymomas grow slowly, often cause autoimmune diseases such as myasthenia gravis, and are usually cured by surgery; thymic carcinomas behave like other aggressive cancers and have few effective drugs."},{"id":"pleuropulmonary-blastoma","kind":"cancer","name":"Childhood lung and airway tumours (pleuropulmonary blastoma, tracheobronchial tumours)","route":"/cancers/pleuropulmonary-blastoma/","tldr":"Primary lung tumours in children are rare and unlike adult lung cancer. Pleuropulmonary blastoma starts as a lung cyst in infants and results from a faulty DICER1 gene that also predisposes to thyroid, ovarian and kidney tumours; removing cysts early, guided by an international registry and family gene testing, prevents progression to the aggressive solid forms."},{"id":"thymoma","kind":"cancer","name":"Thymoma (WHO types A, AB, B1, B2 and B3)","route":"/cancers/thymoma/","tldr":"Thymoma is the slower-growing kind of thymic epithelial tumour, an indolent cancer of the thymus gland behind the breastbone that often announces itself through the autoimmune disease myasthenia gravis. Complete surgical removal cures most patients, radiotherapy is added when the tumour has grown through its capsule, and chemotherapy is used to shrink large tumours or control spread in the chest."},{"id":"thymic-carcinoma","kind":"cancer","name":"Thymic carcinoma","route":"/cancers/thymic-carcinoma/","tldr":"Thymic carcinoma is the aggressive kind of thymic epithelial tumour, a cancer of the thymus that behaves like carcinoma elsewhere and has often spread when found. Surgery is attempted when possible, carboplatin with paclitaxel is the usual chemotherapy, and sunitinib, lenvatinib and the PD-1 antibody pembrolizumab have shown responses in trials, with lenvatinib approved in Japan."}]}