{"slug":"tumor-suppressor","tag":"tumor-suppressor","variants":["tumor-suppressor"],"description":"No description yet","count":1,"kinds":{"target":1},"related":[{"slug":"biomarker-parent","tag":"biomarker-parent","shared":1}],"records":[{"id":"pten","kind":"target","name":"PTEN","route":"/targets/pten/","tldr":"PTEN is the brake on the PI3K growth pathway; when a tumour loses it the pathway runs unchecked, which is why PTEN loss now selects patients for the AKT inhibitor capivasertib."}]}