{"slug":"unproven","tag":"unproven","variants":["unproven"],"description":"No description yet","count":6,"kinds":{"technology":6},"related":[{"slug":"rejuvenation","tag":"rejuvenation","shared":6},{"slug":"survivorship","tag":"survivorship","shared":6},{"slug":"regulator-warning","tag":"regulator-warning","shared":4},{"slug":"hormones","tag":"hormones","shared":1},{"slug":"supplement","tag":"supplement","shared":1}],"records":[{"id":"rejuv-frontier-stem-cell-tourism","kind":"technology","name":"Stem cell clinics and stem cell tourism","route":"/technologies/rejuv-frontier-stem-cell-tourism/","status":"emerging","tldr":"Clinics at home and abroad sell stem cell infusions and injections to people finishing cancer treatment. The FDA has recorded blindness, tumour formation and infections from these products, and says plainly that if you are being charged for one outside a clinical trial you are likely being deceived. Two of the harms are written up in the New England Journal of Medicine."},{"id":"rejuv-frontier-exosome-injections","kind":"technology","name":"Exosome injections","route":"/technologies/rejuv-frontier-exosome-injections/","status":"preclinical","tldr":"Exosomes are real biology and a serious research field. Exosome injections sold in clinics are neither. There are no approved exosome products anywhere, and the FDA issued a public safety notification after patients in Nebraska were seriously harmed by them."},{"id":"rejuv-frontier-unlicensed-peptides","kind":"technology","name":"Unlicensed peptides sold for recovery","route":"/technologies/rejuv-frontier-unlicensed-peptides/","status":"preclinical","tldr":"BPC-157, ipamorelin, thymosin, CJC-1295 and the rest are sold online and by clinics for healing, energy and recovery after treatment. The FDA has placed several of them on the list of substances that may present significant safety risks in compounding, and names immunogenicity, impurities and, for some, deaths in studies."},{"id":"rejuv-frontier-nad-infusions","kind":"technology","name":"Intravenous NAD+ drips","route":"/technologies/rejuv-frontier-nad-infusions/","status":"emerging","tldr":"An NAD+ drip takes several hours, is sold in courses, and has never been tested against placebo for anything a cancer survivor would recognise. The published human literature on intravenous NAD+ amounts to retrospective series and narrative reviews."},{"id":"rejuv-frontier-ozone-therapy","kind":"technology","name":"Ozone therapy","route":"/technologies/rejuv-frontier-ozone-therapy/","status":"emerging","tldr":"Ozone is sold to survivors as an infusion of ozonated blood, a rectal insufflation or an injection, for immunity, energy and detoxification. The United States regulation on the subject opens with a sentence worth reading in full: \"Ozone is a toxic gas with no known useful medical application in specific, adjunctive, or preventive therapy.\""},{"id":"rejuv-frontier-hormone-pellets","kind":"technology","name":"Compounded hormone pellets","route":"/technologies/rejuv-frontier-hormone-pellets/","status":"emerging","tldr":"Pellets of compounded oestrogen and testosterone are implanted under the skin and sold as a way to feel young again. The National Academies reviewed the evidence and told prescribers to restrict their use: the claim that compounded preparations are safer or more effective than approved hormone products is not supported, and nobody checks what is in them."}]}