[{"id":"paper-nhs-galleri-design-cancers-2022","kind":"paper","name":"NHS-Galleri: design of the largest randomised trial of a multi-cancer blood test","route":"/key-papers/paper-nhs-galleri-design-cancers-2022/","commit":"0bdbdae6c6","date":"2026-09-09","author":"Jude Gomila","message":"Editing pass: every TL;DR and summary stands alone","file":"src/data/key-papers/prevention-detection-biology.ts","type":"changed","fields":[{"field":"tldr","before":"\"The protocol for a 140,000-person randomised trial in England testing whether three annual Galleri blood tests reduce late-stage (III-IV) cancer diagnoses, the first MCED trial powered for a stage-shift endpoint.\"","after":"\"The NHS-Galleri design paper is the protocol for a 140,000-person randomised trial in England testing whether three annual Galleri blood tests reduce late-stage (III-IV) cancer diagnoses, the first MCED trial powered..."},{"field":"whatItMeans","before":"\"This is the trial that will decide whether a blood test for many cancers at once should be offered by a health system. Its endpoint is a reduction in late-stage cancer rather than deaths, so even a positive result le...","after":"\"NHS-Galleri is the trial that will decide whether a blood test for many cancers at once should be offered by a health system. Its endpoint is a reduction in late-stage cancer rather than deaths, so even a positive re..."}]},{"id":"paper-nhs-galleri-design-cancers-2022","kind":"paper","name":"NHS-Galleri: design of the largest randomised trial of a multi-cancer blood test","route":"/key-papers/paper-nhs-galleri-design-cancers-2022/","commit":"168ea7d7f3","date":"2026-09-08","author":"Jude Gomila","message":"Key papers: prevention, detection, supportive care and foundational biology","file":"src/data/key-papers/prevention-detection-biology.ts","type":"added","fields":[{"field":"id"},{"field":"name"},{"field":"journal"},{"field":"year"},{"field":"doi"},{"field":"authors"},{"field":"paperType"},{"field":"participants"},{"field":"changedPractice"},{"field":"tldr"},{"field":"summary"},{"field":"findings"},{"field":"whatItMeans"},{"field":"caveats"},{"field":"links"},{"field":"sections"},{"field":"technologies"},{"field":"drugs"},{"field":"trials"},{"field":"terms"},{"field":"related"},{"field":"bottlenecks"}]}]