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Systematically test ways to open up the shut-out tumours, measured with spatial maps.","via":[{"id":"oncolytic-virus","kind":"technology","name":"Oncolytic viruses","route":"/technologies/oncolytic-virus/"}]}],"manufacturing":{"sites":[{"id":"kite-frederick","name":"Kite Frederick","operator":"Kite (Gilead)","operatorRoute":"/companies/gilead/","ownership":"in-house","city":"Frederick, Maryland","country":"US","capabilities":["cell-therapy","viral-vector"],"capabilityLabels":["Cell therapy","Viral vector"],"drugs":[{"id":"axicabtagene-ciloleucel","kind":"drug","name":"Axicabtagene ciloleucel","route":"/drugs/axicabtagene-ciloleucel/"}],"source":{"label":"Kite manufacturing","url":"https://www.kitepharma.com/"}},{"id":"miltenyi-bergisch-gladbach","name":"Miltenyi Biotec","operator":"Miltenyi Biotec","operatorRoute":"/companies/miltenyi-biotec/","ownership":"cdmo","city":"Bergisch Gladbach","country":"DE","capabilities":["cell-therapy","viral-vector"],"capabilityLabels":["Cell therapy","Viral vector"],"drugs":[],"source":{"label":"Miltenyi Biotec","url":"https://www.miltenyibiotec.com/"}},{"id":"oxford-biomedica-oxford","name":"Oxford Biomedica Oxbox","operator":"Oxford Biomedica","operatorRoute":"/companies/oxford-biomedica/","ownership":"cdmo","city":"Oxford","country":"GB","capabilities":["viral-vector"],"capabilityLabels":["Viral vector"],"drugs":[],"source":{"label":"Oxford Biomedica","url":"https://www.oxb.com/"}}],"capabilities":["Viral vector"],"chain":{"id":"cell-therapy","name":"Cell therapy","summary":"Apheresis, vector, closed manufacturing, cryopreservation and chain of identity, release testing, point of care and allogeneic banks.","route":"/manufacturing/#chain-cell-therapy","technologies":[{"id":"apheresis-starting-material","kind":"technology","name":"Apheresis and starting-material collection","route":"/technologies/apheresis-starting-material/"},{"id":"viral-vector-manufacturing","kind":"technology","name":"Viral vector manufacturing (lentiviral, retroviral, AAV)","route":"/technologies/viral-vector-manufacturing/"},{"id":"car-t-manufacturing-process","kind":"technology","name":"Autologous CAR-T manufacturing, batch by batch","route":"/technologies/car-t-manufacturing-process/"},{"id":"closed-automated-cell-manufacturing","kind":"technology","name":"Closed automated cell-therapy manufacturing","route":"/technologies/closed-automated-cell-manufacturing/"},{"id":"cell-therapy-cold-chain","kind":"technology","name":"Cryopreservation and cell-therapy cold chain","route":"/technologies/cell-therapy-cold-chain/"},{"id":"cell-therapy-orchestration-software","kind":"technology","name":"Cell-therapy orchestration and chain-of-identity software","route":"/technologies/cell-therapy-orchestration-software/"},{"id":"cell-therapy-release-testing","kind":"technology","name":"Cell-therapy release and potency testing","route":"/technologies/cell-therapy-release-testing/"},{"id":"point-of-care-cell-manufacturing","kind":"technology","name":"Point-of-care and decentralised cell manufacturing","route":"/technologies/point-of-care-cell-manufacturing/"},{"id":"allogeneic-cell-banks","kind":"technology","name":"Allogeneic cell banks: one donor, hundreds of doses","route":"/technologies/allogeneic-cell-banks/"}],"companies":[{"id":"novartis","kind":"company","name":"Novartis","route":"/companies/novartis/"},{"id":"gilead","kind":"company","name":"Gilead Sciences (incl. Kite)","route":"/companies/gilead/"},{"id":"bms","kind":"company","name":"Bristol Myers Squibb","route":"/companies/bms/"},{"id":"legend-biotech","kind":"company","name":"Legend Biotech","route":"/companies/legend-biotech/"},{"id":"autolus","kind":"company","name":"Autolus Therapeutics","route":"/companies/autolus/"},{"id":"oxford-biomedica","kind":"company","name":"OXB (Oxford Biomedica)","route":"/companies/oxford-biomedica/"},{"id":"miltenyi-biotec","kind":"company","name":"Miltenyi Biotec","route":"/companies/miltenyi-biotec/"},{"id":"cytiva","kind":"company","name":"Cytiva (Danaher)","route":"/companies/cytiva/"},{"id":"lonza","kind":"company","name":"Lonza","route":"/companies/lonza/"},{"id":"cellares","kind":"company","name":"Cellares","route":"/companies/cellares/"},{"id":"cryoport","kind":"company","name":"Cryoport","route":"/companies/cryoport/"},{"id":"terumo-bct","kind":"company","name":"Terumo Blood and Cell Technologies","route":"/companies/terumo-bct/"},{"id":"cellectis","kind":"company","name":"Cellectis","route":"/companies/cellectis/"},{"id":"allogene","kind":"company","name":"Allogene Therapeutics","route":"/companies/allogene/"},{"id":"immunoact","kind":"company","name":"ImmunoACT","route":"/companies/immunoact/"}],"products":[{"id":"tisagenlecleucel","kind":"drug","name":"Tisagenlecleucel","route":"/drugs/tisagenlecleucel/"},{"id":"axicabtagene-ciloleucel","kind":"drug","name":"Axicabtagene ciloleucel","route":"/drugs/axicabtagene-ciloleucel/"},{"id":"lisocabtagene-maraleucel","kind":"drug","name":"Lisocabtagene maraleucel","route":"/drugs/lisocabtagene-maraleucel/"},{"id":"idecabtagene-vicleucel","kind":"drug","name":"Idecabtagene vicleucel","route":"/drugs/idecabtagene-vicleucel/"},{"id":"ciltacabtagene-autoleucel","kind":"drug","name":"Ciltacabtagene autoleucel","route":"/drugs/ciltacabtagene-autoleucel/"},{"id":"obecabtagene-autoleucel","kind":"drug","name":"Obecabtagene autoleucel","route":"/drugs/obecabtagene-autoleucel/"},{"id":"lifileucel","kind":"drug","name":"Lifileucel","route":"/drugs/lifileucel/"}]},"technologies":[]},"drugs":[{"id":"cretostimogene","kind":"drug","name":"Cretostimogene grenadenorepvec","route":"/drugs/cretostimogene/"},{"id":"h101-oncolytic-adenovirus","kind":"drug","name":"H101 oncolytic adenovirus","route":"/drugs/h101-oncolytic-adenovirus/"},{"id":"olvimulogene-nanivacirepvec","kind":"drug","name":"Olvimulogene nanivacirepvec","route":"/drugs/olvimulogene-nanivacirepvec/"},{"id":"t3011","kind":"drug","name":"T3011","route":"/drugs/t3011/"},{"id":"talimogene-laherparepvec","kind":"drug","name":"Talimogene laherparepvec","route":"/drugs/talimogene-laherparepvec/"},{"id":"theo-260","kind":"drug","name":"THEO-260","route":"/drugs/theo-260/"},{"id":"tilt-123","kind":"drug","name":"TILT-123","route":"/drugs/tilt-123/"},{"id":"vusolimogene-oderparepvec","kind":"drug","name":"Vusolimogene oderparepvec","route":"/drugs/vusolimogene-oderparepvec/"}],"note":"Every section is read from existing corpus records and names them (from, via, exemplars, refs); a section with nothing behind it is empty. Medicines of a format are the open drug engine's (/pipeline/engine/); technologies are listed in src/lib/modular-formats.ts. CC BY-NC 4.0, attribute Data from OnCo (onco.cc). Not medical advice."}