OnCo
ideasIdea

An oncology patent pool for combination trials across companies

Companies would put their cancer drugs into a shared licensing pool so that any qualified investigator can test combinations of drugs from different owners under one standard agreement, with royalties split by a fixed formula.

A voluntary pool, administered by a neutral body on the model of the Medicines Patent Pool and the MPEG patent pools, in which participating companies grant a standard non-exclusive licence for their approved and late-stage oncology agents to be used in combination trials sponsored by academic groups, non-profits or other pool members, with pre-agreed terms for drug supply, data rights, publication and downstream royalty sharing if a combination is approved. Today each combination requires a bespoke negotiation that can take longer than the trial; pooled terms cut that to weeks. Regulators would recognise pool trials as acceptable for combination labelling.

Hypothesis
A pool with at least ten participating companies doubles the number of registered cross-company combination trials involving pooled agents within three years and reduces median contract negotiation time for such trials from over a year to under three months.
Rationale
The Medicines Patent Pool has licensed dozens of HIV, hepatitis C and tuberculosis products through standard terms; standards-essential patent pools show competing firms can agree fixed royalty splits. Combination therapy is where most oncology benefit now comes from and where inter-company friction is greatest.
What would test it
Convene five companies and two academic networks to sign pool terms for a defined set of agents; measure trials initiated and negotiation time against the same companies' prior bilateral combination agreements.
Maturity
speculative
Who has to act
industry
Cost to try
Medium ($1M to $50M)
Years to first evidence
3
Bottlenecks it attacks

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