Signet ring cell carcinoma of the colon and rectum
Prepared with OnCo (onco.cc/prep/colorectal-signet-ring-cell-carcinoma/). Orientation, not medical advice; your team knows your case.
My details
What I know, what is unclear, changes to discuss
Saved in this browserMy questions
8 on the sheet- 1.What is my exact diagnosis, stage, and grade, and which tests established them?
- 2.Which biomarkers have been tested on my tumour (for example Signet ring cells over 50 percent of the tumour, Mismatch repair status, CDH1, RNF43 and SMAD4 alterations, Peritoneal disease on imaging), and what were the results?
- 3.Which subtype is my cancer, and does that change the recommended treatment?
- 4.Is germline (inherited) genetic testing recommended for me or my family?
- 5.For my situation (all stages), which of the standard options do you recommend and why?
- 6.Am I a candidate for FOLFOX (5-FU, leucovorin, oxaliplatin), and what side effects should I expect?
- 7.Would a second opinion at a high-volume centre change anything, and can you help arrange it?
- 8.What supportive care (symptom control, nutrition, exercise, mental health, financial help) is available from the start?
Tests and results to bring
Biomarker results to ask for: Signet ring cells over 50 percent of the tumour, Mismatch repair status, CDH1, RNF43 and SMAD4 alterations (research), Peritoneal disease on imaging.
Bring copies of scan reports, pathology and blood results, and a list of every medicine and supplement.
The treatments I may be offered
- All stages: Treated as the colorectal page by stage and mismatch repair status; no trial in the type. (Colorectal cancer, Colon cancer (adenocarcinoma of the colon), FOLFOX (5-FU, leucovorin, oxaliplatin))
From the standard of care recorded for this cancer; which apply depends on your stage and biomarkers. Ask which the team recommends and why.