OnCo

Sign in to keep your watchlist

Your watched pages live in this browser. Sign in with an email link and OnCo keeps the same list on every device you use. Only your email address and your watchlist are stored.

Living with cancer· Appointment prep

Appointment sheet: Claudin 18.2-positive gastric cancer

One page to bring and write on: your details, the questions for Claudin 18.2-positive gastric cancer plus your own, the words you may hear, what to bring, the treatments the standard of care names, and room for the answers and agreed next steps. What you type stays in this browser. Print it or save it as a PDF. New to all this? Start with the first 60 days. Orientation, not medical advice.

Tick the questions to print

All of this cancer's questions start ticked. Untick what does not apply; ticks are kept in this browser. .

Your own questions

Shared with the prep pack, so questions you add there appear here too.

Print or save as PDF

Use (or Ctrl+P, Cmd+P on a Mac). To keep a copy, choose Save as PDF as the destination in the print dialog. Only the sheet prints; the controls stay on screen. Your typed notes print where you typed them; empty fields print as ruled lines to write on.

Appointment sheet

Claudin 18.2-positive gastric cancer

Prepared with OnCo (onco.cc/prep/gastric-cldn18-2-positive/). Orientation, not medical advice; your team knows your case.

My details

Name
Date of appointment
Hospital and clinician
Who is coming with me

What I know, what is unclear, changes to discuss

Saved in this browser
What I know so far
What is unclear to me
Changes since last time

My questions

16 on the sheet
Newly diagnosed
  1. 1.What is my exact diagnosis, stage, and grade, and which tests established them?
  2. 2.Which biomarkers have been tested on my tumour (for example Claudin 18.2 by immunohistochemistry, HER2, PD-L1 combined positive score, Claudin 18.2 expression in metastases and after prior therapy), and what were the results?
  3. 3.Which subtype is my cancer, and does that change the recommended treatment?
  4. 4.Is germline (inherited) genetic testing recommended for me or my family?
Advanced, first line
  1. 5.For my situation (advanced, first line), which of the standard options do you recommend and why?
  2. 6.Am I a candidate for Zolbetuximab, FOLFOX (5-FU, leucovorin, oxaliplatin), CAPOX (capecitabine, oxaliplatin) or related drugs, and what side effects should I expect?
  3. 7.How do the results of SPOTLIGHT & GLOW apply to someone like me?
Second line
  1. 8.For my situation (second line), which of the standard options do you recommend and why?
  2. 9.Am I a candidate for Ramucirumab, Paclitaxel / nab-paclitaxel, Sonesitatug vedotin or related drugs, and what side effects should I expect?
Toxicity management
  1. 10.For my situation (toxicity management), which of the standard options do you recommend and why?
  2. 11.Am I a candidate for Zolbetuximab, and what side effects should I expect?
Any stage
  1. 12.Are there clinical trials I could join, for example of Sonesitatug vedotin, Satricabtagene autoleucel, LM-302, ASP2138?
  2. 13.Would a second opinion at a high-volume centre change anything, and can you help arrange it?
  3. 14.What supportive care (symptom control, nutrition, exercise, mental health, financial help) is available from the start?
  4. 15.I read that “Whether zolbetuximab or PD-1 blockade should come first when both PD-L1 and claudin 18.2 are positive”. How does that affect my plan?
  5. 16.I read that “Tumours below the 75 percent threshold have no approved claudin 18.2 therapy”. How does that affect my plan?

Tests and results to bring

Biomarker results to ask for: Claudin 18.2 by immunohistochemistry (VENTANA 43-14A; 75 percent threshold), HER2 (must be negative for zolbetuximab), PD-L1 combined positive score, Claudin 18.2 expression in metastases and after prior therapy.

Scans and tests linked to this cancer: Companion diagnostics.

Bring copies of scan reports, pathology and blood results, and a list of every medicine and supplement.

The treatments I may be offered

From the standard of care recorded for this cancer; which apply depends on your stage and biomarkers. Ask which the team recommends and why.

Answers and next steps

Saved in this browser
What I was told
Agreed next steps, dates and who to call